Active GMP Pass Box for Cleanroom Applications
The DATAPHARM active material transfer pass box is used in pharmaceutical, biotechnology, and laboratory facilities where controlled transfer of components between areas with different cleanliness levels is required.
The system operates on the principle of unidirectional vertical airflow: purified air passes through an H14 HEPA filter and is evenly supplied into the internal chamber volume, creating a local protection zone and preventing particle transfer between rooms.
Excess airflow is directed toward the less clean area, maintaining the correct pressure cascade and reducing the risk of reverse contamination.
⚙️ Construction and Features
The pass box housing is manufactured from AISI 304 stainless steel with surfaces adapted for operation in GMP environments.
☝️ The design provides:
- minimal contamination accumulation zones
- convenient access for sanitation and cleaning
- stable operation in continuous production cycles
- high chamber tightness
The system is equipped with:
- Ebmpapst fan
- H14 HEPA filter
- electromagnetic door interlock system
- status light indicators
- MAGNEHELIC differential pressure gauge
- Clamp DIN 32676 validation ports
✔️ Door Interlock System
The pass box is equipped with an electronic interlock system preventing simultaneous opening of doors on both sides. This maintains the required pressure cascade between rooms and prevents uncontrolled air exchange.
Doors are equipped with:
- electromagnetic locks
- inspection windows
- status light indicators
🔧 Technical Specifications:
- Installation Type: Floor-standing
- Airflow Direction:Vertical
- Average Air Velocity: 0.45 m/s ±20%
- Filtration Class: HEPA H14
- Filtration Efficiency: 99.995%
- Filtration Stages: 2
- Power Supply: 380 V / 50 Hz
- Power Consumption: 1.27 kW
- Dimensions: 664 × 724 × 2000 mm
- Material: AISI 304 stainless steel
✅ Advantages:
- reduced risk of cross-contamination
- stable vertical airflow
- GMP-compliant design
- integration into cleanroom systems
- high chamber tightness
- easy sanitation and cleaning
- customized project adaptation
- possibility of individual automation solutions
📌 Active pass boxes are used in:
- pharmaceutical cleanrooms
- sterile production areas
- laboratories
- biotechnology facilities
- raw material preparation zones
- GMP packaging lines
DATAPHARM manufactures active GMP pass boxes in accordance with cleanroom engineering requirements, industrial automation standards, and pharmaceutical regulations. Equipment configuration is individually adapted to the customer’s facility and technological process requirements.